21 June 2025, Geneva
Minor revisions added on 22 June 2025 to add updated location information, and attack details.
The United States has carried out coordinated airstrikes on Iranian military and nuclear-related infrastructure, following months of rising tension. Targets reportedly included three sites tied to Iran’s nuclear program: Fordo, Natanz and Isfahan. The attack was carried out using more than two dozen Tomahawk cruises missiles and more than a dozen bunker busting bombs (GBU-57).
According to a recent briefing by ISRS’s Dr. Brigham McCown, RDML, USMS, Iran’s current uranium enrichment levels, reported at 60%, represent a clear deviation from civilian use and a dangerous proximity to weapons-grade material:
“Iran has enriched uranium to at least 60%, far beyond the 3-5% required for civilian facilities... There is no civil use for uranium at that level”
— Dr. Brigham A. McCown
McCown further explains the risk:
“Weapons-grade uranium is in the 80-90% range, and getting there would take two weeks, or even less for a dirty bomb. This signals potential military intentions or bargaining pressure”
He emphasizes that even research reactors use only 20–25% enrichment, reinforcing the conclusion that 60% enrichment constitutes a strategic provocation, not a peaceful program.
1. Disrupt Weapons Breakout Timeline:
By targeting facilities associated with 60% enriched uranium, the U.S. is imposing direct costs on Iran’s latent nuclear weapons capability, disrupting what analysts describe as the “last mile” to weapons-grade material.
2. Re-establish Deterrence:
This operation sends a clear signal not only to Iran but also to Russia, North Korea, and other adversarial states:
Nuclear brinkmanship will not go unanswered.
Enforcement is no longer just rhetorical.
Nonproliferation red lines will be defended with kinetic force if necessary.
“Removing the facilities diplomatically or by force, if necessary, is essential... especially with Actors who do not respect the Rule of Law.”
— McCown
3. Reassert Global Norms:
The strike may also be read as a warning to rogue regimes exploiting international inaction. It aims to reinforce the credibility of IAEA frameworks and re-anchor U.S. leadership in nonproliferation enforcement, after years of contested withdrawals and weak signaling.
Middle East Tension Spike:
Expect retaliation from Iran or its proxies. Gulf nations may elevate alert levels, and Israeli missile defense systems are reportedly on high readiness.
Strait of Hormuz Risk:
Iran may leverage its asymmetric naval capabilities to disrupt global shipping, especially oil and gas tankers. Iran’s parliament voting on just such a motion following the attack. If attempted, the closure would signal a serious escalation in the conflict. Such a closure would send oil prices high, but would not significantly impact Israel or the U.S.
Cyber Retaliation:
APT33 and APT35 may activate cyber retaliation protocols targeting U.S. critical infrastructure and private-sector assets.
Information War:
Iranian state media and influence networks are pushing narratives of U.S. aggression. Expect surge in disinformation and emotionally charged propaganda, especially in Arabic, Farsi, and Russian digital ecosystems.
For Allied Governments:
Prepare for retaliatory proxy activity in Iraq, Syria, Lebanon, and Yemen.
Fortify cyber defenses and activate cross-border intel sharing.
Convene emergency sessions with IAEA and UNSC allies.
For Civil Society & Media:
Monitor disinformation framing this as an unprovoked act of war.
Reaffirm the importance of nuclear nonproliferation and JCPOA constraints.
For Strategic Analysts:
Track Russian and Chinese media responses as this strike will likely factor into their deterrence calculus.
Reassess nuclear deterrence thresholds in light of kinetic precedent.
ISRS is currently monitoring:
Iranian ballistic and cyber activity
Escalation by regional proxies
Global diplomatic fallout
Disinformation campaigns
Further analysis will follow as battlefield effects, strategic intent, and retaliatory options crystallize.
Contact ISRS for custom briefings, partner intelligence synthesis, or technical insights at: info@isrs.ngo
Prepared by:
ISRS Strategic Advisory & Risk Analysis Unit
Geneva, Switzerland
About ISRS
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